(Senior) Scientist - High Throughput Screening

Client Scientific

Location Kraków, Poland

Region Kraków

Offer description

Selvita is a global integrated drug discovery partner for the pharmaceutical and biotechnology industries with offices in Cambridge, UK, Greater Boston Area, San Francisco Bay Area, as well as, Krakow and Poznan, Poland. The company offers drug discovery support at every stage of the early discovery phase up to the preclinical research phase.

Due to constant development, currently, we are looking for enthusiastic and highly motivated Scientists and Senior Scientists with demonstrated expertise in biochemical and cell-based assay development, miniaturization and screening to join and help to build our Core Assay Development & Screening Unit within Cell and Molecular Biology Department and support Selvita’s drug discovery projects.

At Selvita, we work knowing that the research we do, makes an impact on human lives.

Key responsibilities

Assistance in the design and construction of the HTS platform at Selvita
Developing target-relevant biochemical and cell-based assays including optimization, validation and troubleshooting (screening assay robustness, sensitivity, reproducibility)
Evaluation of the novel cell-based screening initiatives for implementation into the group portfolio
Converting assays into HTS format - assay miniaturization to 384-well / 1536-well format
Design and implementation of the key in vitro pharmacology experiments for low-throughput compound profiling (efficacy, selectivity, mechanism of action)
Performing HT screens and hit identification
Statistical analysis, reporting and critical data evaluation for providing a scientific contribution to internal drug discovery projects
Ensuring all tasks and responsibilities are performed according to industry-leading scientific and ethical standards and accurately documented in the lab electronic notebook system

Your background

MSc in pharmacology, molecular biology, biotechnology or similar discipline with minimum 2 years of experience in a biotech/pharma setting or Ph.D. in relevant biological sciences
Good knowledge of in vitro pharmacology concepts with a strong focus on at least one of the following areas: intracellular signaling, cancer metabolism, immunology, CNS
Experience in working with cell lines and cell-based assays in microplate format
Prior experience with mid-to-high throughput screening, liquid handling devices and lab automation will be a plus
Analytical and problem-solving skills with proven troubleshooting experience
Well-developed multi-tasking, flexibility and team working skills
scientific presentation and interpersonal communication skills
Fluency in English

Your Benefits Package

Extensive research facilities and modern laboratories.
Daily cooperation and know-how exchange with an experienced research team.
Long-term cooperation based on stable employment conditions and a clear career path.
Support of experienced mentors with international scientific experience.
Benefits: private medical care, on-site fitness zone & subsidized sports card, lunch benefits & fruits in the office, on-site, subsidized kindergarten.
Support in legalization and relocation from abroad.
Language courses (English & Polish).
Complex training programs.
Support & incentive bonus for completing Ph.D.
Various sports initiatives.