(Senior) Scientist - High Throughput Screening

Client Scientific
Location Kraków, Poland
Region Kraków
Offer description

Selvita is a global integrated service provider with laboratories in Poland (Krakow, Poznan, and Wroclaw), Croatia (Zagreb), and offices in Cambridge, UK, as well as the Greater Boston Area and San Francisco Bay Area in the US. Our company is dedicated to delivering comprehensive solutions that support our international clients in drug discovery and drug development.

As one of the largest preclinical contract research organizations in Europe, Selvita is driven by a clear mission: to bridge the gap between early drug discovery and the clinical stage of drug development.

At Selvita, we value partnership, excellence, passion, commitment, and integrity. We build strong, collaborative relationships with our clients and commit to the highest standards of quality. We fuel our pursuit of innovative solutions with enthusiasm, advance drug development with focused dedication, and ensure honesty and transparency in all our work. 

Due to constant development, currently, we are looking for enthusiastic and highly motivated Scientists and Senior Scientists with demonstrated expertise in biochemical and cell-based assay development, miniaturization and screening to join and help to build our Core Assay Development & Screening Unit within Cell and Molecular Biology Department and support Selvita’s drug discovery projects.

Join us at Selvita, where these values guide our mission to advance drug discovery to the clinical stage of drug development.

Key responsibilities
  • Assistance in the design and construction of the HTS platform at Selvita
  • Developing target-relevant biochemical and cell-based assays including optimization, validation and troubleshooting (screening assay robustness, sensitivity, reproducibility)
  • Evaluation of the novel cell-based screening initiatives for implementation into the group portfolio
  • Converting assays into HTS format - assay miniaturization to 384-well / 1536-well format
  • Design and implementation of the key in vitro pharmacology experiments for low-throughput compound profiling (efficacy, selectivity, mechanism of action)
  • Performing HT screens and hit identification
  • Statistical analysis, reporting and critical data evaluation for providing a scientific contribution to internal drug discovery projects
  • Ensuring all tasks and responsibilities are performed according to industry-leading scientific and ethical standards and accurately documented in the lab electronic notebook system
Your background
  • MSc in pharmacology, molecular biology, biotechnology or similar discipline with minimum 2 years of experience in a biotech/pharma setting or Ph.D. in relevant biological sciences
  • Good knowledge of in vitro pharmacology concepts with a strong focus on at least one of the following areas: intracellular signaling, cancer metabolism, immunology, CNS
  • Experience in working with cell lines and cell-based assays in microplate format
  • Prior experience with mid-to-high throughput screening, liquid handling devices and lab automation will be a plus
  • Analytical and problem-solving skills with proven troubleshooting experience
  • Well-developed multi-tasking, flexibility and team working skills
  • scientific presentation and interpersonal communication skills
  • Fluency in English
Your Benefits Package
  • Working in world-class extensive research facilities and modern laboratories.
  • Daily cooperation and know-how exchange with scientific experts.
  • Additional benefits: a prepaid lunch card, private medical care, subsidized sports card, and office fruit provision.
  • Internal Development initiatives including soft & leadership skills training programs.
  • Recognition Program.
  • Employee Referral Program.
  • English & Polish language courses.
  • Support & incentive bonus for completing Ph.D.
  • Support in legalization process and relocation package.
  • Various sports and engagement initiatives.
Last modified Thursday, July 18, 2024