Principal Scientist/Senior Scientist - Bioanalysis (m/f)

Client Scientific

Location Zagreb, Croatia

Region Zagreb, Croatia

Offer description

Selvita is a global integrated drug discovery partner for the pharmaceutical and biotechnology industries with laboratories in Poland (Krakow & Poznan) and Croatia (Zagreb) and offices in Cambridge, UK, Greater Boston Area & San Francisco Bay Area in the US. The company offers drug discovery support at every stage of the early discovery phase up to the preclinical research phase.

Selvita in Zagreb is a scientific research organization with a long research tradition in the fields of biology, chemistry, biomedicine, veterinary medicine, pharmacy and related scientific fields, with the purpose of discovering new chemical and biological entities intended for the treatment of various diseases. We are a service organization; our scientists are working on projects, in collaboration with external partners, aimed at discovering a new drug or establishing test systems and platforms that improve the predictability of the research process.

Within our Drug Metabolism and Pharmacokinetics (DMPK) department we are looking for a motivated and detail-oriented scientist to join us in the role of Principal Scientist/Senior Scientist - Bioanalysis (m/f).

Key Responsibilities

The Bioanalytical team within DMPK plays a central role in evaluating test compounds by delivering quantitative and qualitative data for both in vitro and in vivo studies, along with physicochemical characterization across a range of modalities. The group develops and applies LC-MS/MS methods, performs complex sample analysis and interprets data to support scientific decision-making. Continuous improvement is a core focus, including implementation of automation, advanced extraction techniques, and high-throughput LC-MS workflows.

Key responsibilities:

Lead the development, optimization, and implementation of LC-MS/MS bioanalytical methods for small molecules, peptides, biomarkers, and metabolites in complex biological matrices
Drive innovation by evaluating and implementing new analytical technologies and methodologies to address challenging assay needs
Oversee and actively contribute to laboratory activities, including sample preparation, data generation and instrument operation
Provide technical leadership, mentoring and hands-on guidance to junior scientists within the team

Troubleshoot complex analytical and instrumentation issues, ensuring robust and reliable assay performance
Contribute to metabolite identification and structural elucidation in collaboration with DMPK and medicinal chemistry teams
Assist in the preparation of study proposals, statements of work, and cost estimates, coordinate timelines and resources for project execution
Identify opportunities to expand scientific capabilities and contribute to strategic development of bioanalytical services
Pursue ongoing professional development by engaging in scientific training, presenting data, and staying current with advancements in the field

Your Background

Graduate degree (MSc or PhD) in Analytical Chemistry, Chemistry, Pharmacy, Biotechnology, or a related field
Solid experience in LC-MS/MS based bioanalysis including method development and troubleshooting
Strong understanding of sample preparation techniques and bioanalytical workflows
Proven ability to work independently while contributing to team and project leadership
Computing skills, including word processing and use of spreadsheets (e.g., Microsoft Office packages and Microsoft Project)

What we offer

A key scientific role with influence on bioanalytical strategy and project outcomes
Opportunities to lead and shape bioanalytical approaches within drug discovery programs
Access to advanced analytical technologies and laboratory automation
A collaborative, international environment with strong scientific exchange
Ongoing training and professional development to support your career growth